Asked my CCW instructor a similar hypothetical question.
I was told - paraphrased- No, you cannot defend property with deadly force (in Ohio). Purse, wallet, car, television, etc. It the perp is getting away, and did not attempt to or succeed in harming you or a family member in the process, you cannot legally open fire. There is, however, no law regulating a good pistol-whipping (or similar "nonlethal" alternative) to subdue an escaping felon. You may, however, want to use a weapon with fixed sights