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Will the 1173 foot pounds of 1 ounce of lead(at the muzzle), even though the pellets are starting to disperse at 15 feet, knock the dog poop out of the perp?
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If you shoot anyone (not wearing body armor) center-mass with a 12ga load of #8 or larger shot at 15 feet I highly doubt they'd walk away or do any fighting back. And whoever's left after all the statements are taken will have a mell of a hess to clean up.
That said, I don't load my home defense shotgun with anything smaller than #4 buck.