I have been shooting XP's for years. Under the right conditions, they are every bit as accurate as a rifle of similar barrel length. As to hunting with any handgun, keep in mind that you will rarely have an opportunity for the perfect setup prior to a shot. You will need considerable practice. However, if you do your part, the XP will do the rest.
As to chambering, a 243 would be fine, but I would suggest you consider the new Remington 260. Hope this helps
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