Bottom Gun, I handload and have been doing so for many years, for my various firearms. I have been lucky enough to kill quite a few deer and elk, antelope and Black bear.
I've always found that, for me, the Nosler Partition bullets, and the Hornady Interlocks, work best in my rifles, when shooting game.
Also, anectodal, a good friend of mine who is a fine hunter and very good shot, took a .300 Win. Mag., Fail Safe factory ammo, to B.C., for griz, three years ago, drilled one at about 90 yards, and he and his guide lost the bear. Searched and searched, but couldn't find it. My friend said he made a good killing shot, and I believe him. He was very disappointed in the Fail Safe bullet.
I've used Grand Slams for target practice, found them accurate in my rifles, but don't know how they'd perform on game animals.
I don't use Fail Safe. For hunting, Noslers and Hornady Interlocks for me. FWIW. J.B.
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