I reload 8 handgun calibers (if you consider .38/.357 and .44 spc/.44 magnum two calibers each) with a hand press and and do it all out of my desk, which also contains a computer, bookshelf, memorabilia and other items. I store bulk supplies in various places around the house and use the deep desk drawer for the most-used stuff, including small tupperware containers for powder (I hand-dip everything). I've reloaded 13K+ rounds in less than two years. When the drawers are closed you couldn't tell it's a reloading station at all, at my wife's insistence.
You'd be amazed at how economically space can be utilized when necessary.