Hands down, goin' away - the
Ruger SR9 or SR9c, depending whether or not you intend to use it for concealed carry.
Mine is obviously more accurate than I am. Smooth trigger, about 5 lb trigger pull; eats anything I feed it, so far, and that's 8 or 10 different brands and different types of bullets. If you want
LOTS of firepower, they come with a 10-shot and a 17-shot magazine. Pretty nifty, I think.
Price wise - I got mine from a local dealer who works out of his home - about $350.
I would second the motion for 9mm. For all intents and purposes, a decent brand of ammo with a good hollowpoint will serve you very nicely for self-defense and the price will allow you to do a
LOT more shooting for fun, which you need to do anyway.