I think what Hornady is trying to say is that H-110 is a hard powder to ignite and it's possible that without a magnum primer and a light load the shot may "squib" and not push the bullet out of the barrel and when firing the next one...................well you know what happens then.
Just do not go under the recommended MINIMUM load that is published in the bookwith whatever primer is recommended and you will be OK.
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