I got a S&W Model 29 that prefers the Sierra 240JHC over 21.5grns of H110 w/CCI350 primer and a good crimp.
I do have a plinker load of 3grns of Herco over a mag primer and a 240grn cast bullet (whomever is least expensive by the 500) sitting as far down as my seating die can get it.
Smedley
Crimp em in at the bench, if necessary, and launch with the srtike of the hammer