ive never killed a deer with my .22-250, but i have killed a number of them with the .222rem and a 50 gr soft point, the same load i used on groundhog, i kept shots under 100 yards, and shot them in he neck or head just to be safe, with the modern bullets like the 60fr partition and 75gr sirocco, i would have no problem using a .22-250 with normal bullet placement.
ken
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