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Its important to understand that there is no "one shot-stop gurentee" with any handgun cartridge, even a .45. Your best bet is to place your shots into 'key areas' of the threat.
Unless your in the military and the situation calls for it, you should never need to just empty the magazine blindly to supress an enemy. As a civillian you will need to be able to shoot fast and hard especially upclose, but you had better keep those rounds on target as best as you can. A well trained shooter can keep all his /her shots on target at moderate ranges about as fast as they can pull the trigger. This can be done with either point shooting or using the sights or a mix of both. You should always see what you need to see if your going to shoot. Just banging off rounds is a liabilty.
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