Speed would be the concern and for that, you need a shotgun with no less than #4's. A more important concern is "WTH" are people doing with large wild animals in their homes? Heck, this lady even stated that she slept with this Chimp. Also note that on the 911 call, she kept asking or requesting that someone bring a gun. Wonder how she really felt about guns for protection, before this incident. Ever notice when self protection programs list what to do, they seldom if ever mention firearms?
We shoud always be aware of neighbors that keep not just wild animals but even certain breeds of dogs. In certain communities certain breeds are forbidden. Had a buddy who was the dog catcher in three of our counties and in one town, he had the authority to shoot any pit bull, on the spot. If it was in a fenced yard, he gave them two days to get rid of it. If it was in the streets, you do the math.
Be Safe !!!