tobnpr says validating trajectory is routine, it's rare that charts or ballistic programs are accurate at longer ranges and need to be "tweaked"
I've used Sierra Bullets software with several of their 30 caliber HPMK's shot from .308's and 30 caliber magnums to get longer range sight settings from "shooting boresight" set on the sights. Once setting the atmospheric conditions and muzzle velocities in the software to what was observed at the range, sight settings based on bullet drop was not off at 300, 600, 800 and 1000 yards by more than 1/2 MOA.
"Shooting boresight;" determined by shooting from position at 100 yards to get initial sight settings, then correct the sight elevation setting for bullet drop at 100 yards plus sight height above bore axis. Using an optical collimator to see the results, the line of sight was never perfectly aligned with the bore axis after doing this.
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