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A long time ago and I can't find it again, I read a study where they compared training with 22s and transitioning to 38s (similar SW revolvers) vs. just starting the 38s and found no difference. Whether this is true - I don't know and haven't seen it since.
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I see one difference....training with thousands of rounds of .22lr is far more economically feasible than using thousands of rounds of centerfire ammo. Less wear & tear on your carry gun, too.