HK P7M8 is as lefty-friendly as they get. HK USP's with decocker safety moved to righthand side is also a possiblilty as mentioned earlier. CZ 85 is labeled as an ambidextrous version of the CZ 75. I am sure there are others worth considering. That said (being left handed), most of the time I carry a Glock and just put up with its right handed layout.