He doesn't want to spend more than $350?
The Ruger P95 or S&W Sigma pistols are both reliable, and they are in that price range. You can get either out the door, and maybe a box of ammo, for that amount.
Whatever he buys he should take it to the range as often as possible to practice and become comfortable with the pistol. If he's new to handguns, and self-defense is his main objective, he needs to be proficient enough to be able to handle his weapon without fumbling around to get off the first shot.
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