Here is the full story of how and what do to by Gaylord:
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It would be sheer folly to make a souped-up .38 load that would be practical in Colt's Official Police or New Service, or in Smith & Wesson's .38-44 Outdoorsman and expect to use it in a "K" frame Smith & Wesson, or in an air-weight revolver.
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Okay according to this K frame and small frame revolvers (made up to 1960) are out. He moves on to say:
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The best all-around police bullet for use in the heavy-frame .38 is made in this way. Use regular .38 brass and .357 Magnum primers. Cast teh blunt-nosed 200-grain bullet, similar in corformation to the Western Super Police bullet out of type metal. Load the cartridge with Unique powder, tailoring the charge to suit the length of the barrel of the weapon. The case should be loaded to produce the velocity of between 1000 and 1200 feet per second. This load will smash armor plate. It is equally effective against car or criminal.
When you buy a gun, make sure that it is strong enough to handle the .38 caliber 200-grain Man-Stopper. Your dealer may have to order these cartridges for you. Thay are worth the trouble. In my shop, we often say that anything less than 200 grains is effeminate
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Now, again if this weight bullet was molded properly into a well made hollow point, it could be an effective round.