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I like .308 for a do it all caliber. Especially if deer will be your primary target. 7mm-08 is just as good and funny as it may seem, easier to find, at least right now. I've killed deer with a .243 as well, and if I was doing any sort of varmint hunting, might consider it, but for majority deer, I'd go a little heavier. Just my two cents.
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