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The Hornady .452 diameter 250 and 300 grain XTP bullets were designed specically for the .45 Colt. IIRC the expansion range is from about 800 to 1200 fps. This will put you in either standard or +P velocity ranges. I haven't tried them in "magnum" level loads.
As a side note: I've found the .45 Colt is at its best using hard cast lead bullets and these would be my choice for hunting loads.
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Artificial intelligence is no match for natural stupidity.
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