Better for what game should be the question. You can't really compare cartridges like that because what may be good for one application won't be as good as the other.
I have a 25-06, and I love it. It's super accurate and works for deer size game on down. The 7mm-08 Rem is a super accurate cartridge as well. For deer size and I guess even elk or moose, a 7mm-08 will be the better choice. If I had to pick one for the bigger game hunting, the 7mm-08 would get the nod. For deer on down, the 25-06 will be probably all you need. The 25-06 will shoot a little flatter with the smaller weight bullets that it has. For varmint hunting, the 25-06 is very popular with some hunters who swear by them as the ultimate coyote round.
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