Yes, you can when my kids and I go I use the .223 for my shooting and they use the .30 cal on the .204,.223,.22, the only thing is the POI's will vary due to the different weight as discussed on .204 ruger.com actually they increase the FPS to appx 15 fps more. I have hearing issues and I can not tell the sound db's from the .223 can vs .30 can but to me the .30 is more effective over the .223 but again thats me.
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