I love both cartridges. When it comes down to brass tacks, neither one has any measurable performance over the other for personal defense with the exception of mag capacity. The level of silliness is astounding when hearing both sides of the argument.
If you're torn, I would pick the .45. I'm only assuming you're not experienced in reloading. If so, I can't stress enough my opinion is learning with .45ACP is far more forgiving of mistakes than .40SW.
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