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It can be done; a few years ago there was some work done with subsonic .45-70 to avoid the transsonic transition at long range. It didn't accomplish much on target and I never saw the muzzle blast mentioned.
In olden times, there were "gallery loads" with the 250 grain "collar button" bullet. You might find some mention of them in an old book.
But "wisper quiet" isn't in it, unless you get a silencer.
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