I am a real man, and I can take it!
Although I did sell my 454 Casul because the loud noise scared my dog. Yeah. Scared my dog.
Seriously, it isn't just about caiber, it's also about load. Gun ergonomics plays a role too. Shoot a bunch before you make any hard decision. I carry a .45 and I'm very comfortable with that. My wife prefers 9mm. I wouldn't want to be in a gunfight with her...
Nio