Lead bullets give less pressure per load than jacketed bullets of the same weight do, so the max load for the XTP should be safe with a cast bullet of the same 300 grains weight. BUT ONLY IN THE SAME TEST GUN!
As with any reloading, begin with the starting (8 grain) load and work up slowly, looking for pressure signs, and also bore leading. If your bullet is not a gas-check design, you may only be able to go to moderate velocities without severe leading, depending on bullet to bore fit. Under no circumstance exceed the 10 grain max load.
In working up, whenever you find a load that is accurate enough for your needs or expectations, stop there. A few extra feet per second is pretty meaningless with a large, heavy slug like the 300 grain 44.
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