We've got four .25-06 rifles in the family and the recipe I have settled on is Remington brass, 115 grain bullets (either SGK or Hornady SST), 50.0 grains of RL22 and WLR primers. This is my stock, go-to load for that caliber. I can't tell you which rifle this group was shot from, simply because we have two Ruger 77s in that caliber, but this group is very representative of this load in any of our four rifles.
I'm sure that I could play with an individual rifle and tighten that group some, adjusting the cartridge OAL to an individual chamber, but because I'm loading for four of these rifles, two Rungers, two Savag, and I generally just load a batch to the standard length.