Get to a range where you can rent guns...and shoot as many as you can...
Figure out what fits your hands the best ( not what fits my hands..)..
Figure out the mfg that gives you the grip angle you like, the kind of trigger you like, the controls you like....what caliber you like ...
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If I were to give you a decent short list of guns to at least consider:
a. A good 1911 ...in 4" and 5" in 9mm and .45 acp
b. A Sig 226 ...( in 9mm probably )...its a full sized double stack gun
c. At least one S&W revolver...K or L frame ( so model 19 or 66 - or in an L frame a 686 ) ...but you posted this in the semi-auto forum
d. Some rimfire guns in .22 lr...at least one model of the Browning Buckmark..
then come back and see us in the morning....