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They used 44-40 on deer all the time 100 years ago.
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44-40 nearly wiped out game animals during the last part of the 19th Century, even though muzzle energy numbers say it couldn't have. The 45 Colt was pretty much just a handgun cartridge until relatively recently, but it performs about as well as the 44-40 does on game animals.
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-light bullets NOT for deer, no penetration light wounding unless short range out of a rifle
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357 is a hard hitting number on animals up to moose size. I still snicker when someone tells me a 357 won't kill a deer because it only develops 500 fpe. 120 years ago, a 32-20 was considered a good deer cartridge. Peoiple killed deer with 300 fpe all the time. Now how did they do that?
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if you focus on energy, standard 45 colt loads equal the 44 special, and that still equals what the 45 acp can do
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Problem with energy charts is that they don't kill animals. If you actually get out and shoot, you will find that many animals die with a lot less than the 1000 fpe gun rag writers say you need. 45 ACP will kill deer dead, trust me. Also pigs. Can't speak for elk or moose, I never tried it.