If you intend to shoot loads that approach the .454 Casull, the "old" model will handle it but you will find that shooting such loads a lot is not fun. The new Vaquero, by design, isn't able to handle such loads and long strings of shooting at the lower power level are enjoyable.
I load for mine using Unique powder and 255 gr. bullets. This makes a very enjoyable load no matter which model you have.
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