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The scary parts is that a human being can kill you before he dies from all the bullets you put in him.
For that reason,you need to shoot calibers of large enough size to at least let him know he's being shot.
You are talking about an encounter with another human being determined to do you harm and he's closing distance on you in likely no more then two seconds.
In that distance,you might get two or three rounds off before he's on you.
This is someone with a knife or a club or just his hands,wacked out -angry as hell.
A person with a handgun is another matter altogehter as you will face exactly what you are trying to defend yourself with.
A person of unknown training using a gun against you of unknown caliber who is trying to kill you-presumably to rob you or who knows-mayber today was the day this guy's -had it with the world day-and you 'unlucked' into his perimeter.
The only thing that will stop your assailant is the ballistic damage you do to him before he can harm you.
If that damage is not sufficient to make him consciously stop his attack-you need to create enough physical damage in his body so he cannot continue his attack.
And human fat acts as a great destabilizer of weak calibers ballisitic performance so the bigger and nastier the bad guy the more ballistic performance you will need to make any change in the bad guys trajectory towards YOU.
You might only have two seconds to do all that.
You want a 22 lr to defend yourself now?
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