I like the following muzzle suppressors.
Gemtech Outback-II
http://www.gem-tech.com/outback.html
SRT Cheyenne XL
http://www.srtarms.com/22can.htm
AAC Pilot
http://www.advanced-armament.com/pro...fire/pilot.asp
SWR Warlock
http://www.swrmfg.com/ProductDetails.asp?ID=17
Browning Buckmark with Bowers CAC22, Ruger 22/45 with Gemtech Outback-II, and P22 with SRT Cheyenne. I suggest the muzzle can over integral -- the suppressor can be moved to any .22lr gun that has a threaded barrel.