I run a few to bounce the machine a bit and make sure the powder is settled as much as it will (have never compared to find out whether this is necessary or not--less time consuming to just assume it does). I then weigh 3 or 4 loads and maybe one about 50 down the line.
The Hornady is boringly consistent for revolver loads. I have found that different batches of the same powder will weigh differently and, too, want to make sure I haven't accidentally miss adjusted something.
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