I have shot a suppressed 50BMG rifle. The suppressor is huge compared to a regular rifle suppressor because of the gas volume produced by 50BMG.
For 50 Beo, you should be able to use a regular rifle style suppressor with the right size hole for .50.
I would recommend contact JET and having them build you what you need. Their cans are significantly lighter and have less POI shift than others that we have tried.
-z
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