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I took many, many deer with my 7 1/2" Ruger Redhawk. Upgraded to a .454 20+ years ago, but still used the .44 for Ohio deer until .454 became legal some years later.
10MM will certainly do the job, but finding factory loads with a more appropriate hunting bullet would be a lot more difficult for 10MM, while quality premium hunting ammo for .44 is readily available on the shelf.
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