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Reduced loads CAN be dangerous. According to ADI/Hodgdon H4895 / AR2206H is the slowest burning powder that ignites uniformly. With it you can use the 60% rule which is, take the maximum listed charge for a cartridge and bullet weight and use 60% of this value to achieve a reduced load. Obviously you can increase from there too.
I've attached the e-mail from ADI/Thales Australia
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