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Although it sounds like this advice is a little too late, I would highly recommend working with much smaller batches to start with, *especially* when testing out new recipes for the first time.
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Absolutely.
Way back when I started, I loaded up 50 rounds of .380, using the starting load for the bullet and powder I had. They were too weak to reliably cycle the Makarov I was shooting at the time. I didn't have a bullet puller at the time, so I was kind of stuck working through that box.
You want to inch your way through the published range. Say, a magazine full for every 2/10 of a grain increase in powder charge. See if there are any problems, or a "sweet spot" where things seem to work very well.
For .40, you want to be mindful of the seating depth warnings. It's a pretty high pressure round.