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I have pretty much subscribed to Elmer Keiths idea that heavier is better. I hunt with my 45LC in a Ruger Blackhawk. I generally have it loaded up to equal a 44 Mag and shoot 300 gr bullets. They just pennetrate better at pistol velocities, much like the old 45-70 blackpowder rounds. It is hard to stop a heavy bullet once it is moving.
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