If I had a Ruger 10/22, I would probably put one of these on it.
http://www.opticsplanet.com/redfield...e-reticle.html
I own two Redfield scopes and I have been very happy with them. I really like the accu-range reticle. With the 4-12 power, I can shoot the heart from a squirrel at 80 yards with .17 HMR. I reccomend the 3-9 because you don't need anything more than that for a 10/22.
Redfield makes great optics, made in America, warrantied for life, great light transmission and clarity. I take out squirrels with deadly precision at any distance that I can see one.
Also consider a good reflex sight, such as a Burris Fastfire. For a 10/22, it would allow you to shoot both eyes open and with a high degree of precision, no magnification though.