I've found from 25 to 40 with filler gets a lot more shots down range during a session. When I 1st got mine I tried the 50 and 60gr loads and didn't hit the target; a 2'by 3' sign board, dropped to 40 and had a nice group and could figure where to hold and start backing up the target, now I can place it out to 50' and still get a group til my arms tire of holding that monster up. I usually switch to my 31cal or 36 cal to finish my round.