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No difference in strength. I have one in .45 ACP and I also handload the .45 Super. I've not tried any .45 Super in it yet, but I don't see that it would be a problem as my .45 Super loads are at least 30K psi loads if not more.
There's an article about a guy using the .45 ACP cylinder and ACP brass to load up 460 Rowland level loads and it worked. I'm not advocating that, but just to say it's been done.
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