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It's my opinion that hydrostatic shock/permanent wound cavitation with a cartridge fired from a handgun (leaving out such things as AR-15 and T/C "handguns", of course) is, in the most generous telling, insignificant to nonexistent. It's certainly nothing I would count on to protect my bacon nor anyone else's.
Consequently, I prefer big, heavy, wide bullets at moderate velocity, to assure a maximum wound diameter and penetration depth.
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