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A good 300-yard bullet for the .243 is the Sierra 85-grain HPBT. I get very tight groups with it, and it is very destructive inside a coyote.
Coyote results can be weird, however. Using a Federal Premium High Energy load in my '06 (165-grain HPBT Sierra at 3,150 ft/sec), I blew a chunk of heart and lower ribs completely out of a coyote at a distance of no more than fifty yards. He spun around a time or two and ran nearly fifty feet before dropping. Even after leaving nearly a pound of goop on the ground!
Other times, similar impact points, DRT. Damfino.
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