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Last year I had to finish a 6 point off with my Glock 21 45acp. I had a good hit on him with my 30-06, right in the vital area. The bullet didn't expand at all it just went through him (20yd shot, probaly not enought distance for expansion). The deer took of like a bolt of lighting and I tried to down him with a second shot from my 30-06 but failed. To make a long story short I tracked the deer down and shot him at close range with my .45acp.
When the .45 hit him he went down like a rock, just crumpled in his tracks. I was using a 185 grain speer gold dot, I got full expansion but no a complete pass through, the bullet stopped at the outer most layer of the hide (I could see the bulge and feel the bullet under the thin layer of hide). If I had used some +p ammo of 200 gain or greater I have no doubt that it would have been a complete pass through.
I feel that a .45 is a capable deer cartridge when used within its proper limitations.
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