When I first got into centerfire, back in 1950, my uncle had a Gebby barrel on a Mauser action, a "Varminter". Remington made a trivial mod to this necked-down .250 Savage and brought it out as the ".22-250". Basically, the Swift and the Varminter are still the most popular high-power .22s, for all that they're older than I am.
To a great extent, it's six of one, half-dozen of the other. They'll both push 50-grain pills to around 3,800 or a tad better, and in my own experience are equally capable of tight groups. 3/8 MOA for five shots is not unreasonable.
In the FWIW department, Phil Sharpe lists a load for the .22 Savage Hi-Power: A 40-grain bullet and a bunch of 2400, for 3,900 ft/sec. Look up the introductory date of the cartridge...
, Art