Pretty much have to go with what
crowbeaner has suggested except that on the In-Lines, I pretty much stay with loose 777 at 90 to 95 grains. Keep in mind that most of my deer shooting is under 60yds. but did take one at 150. Also try a bore button or wonder wad over the powder load. Maxi-Balls are okay but like the group of the Buffalo conicals better. I also like the Maxi-Hunters but they drop off pretty fast. My love is in all M/L's but my passion is in
"Side-Cockers" . However,
"I never tell a man what to do with his money or his wife" 
Be Safe