If you are watching for a used Ruger Vaquero (a good idea) keep in mind that there are two different guns. The original Vaquero had the large sized cylinder, main frame and grip frame. This is why they were offered in .44 Magnum; it's pretty much a Super Blackhawk in different dress. That gun in .357 is plenty hefty.
Later Ruger replaced it with the New Vaquero which is built on a smaller frame. It's designed to be similar in size to a Colt SAA and it's a much handier gun (in my opinion) than the older Vaquero. Some shooters with large hands seek out the Vaquero for its longer grip frame.
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