Disclaimer: I shoot benchrest.
Best accuracy from a factory chamber. Fire form 'em with a starting load, with the bullet jammed hard. Bolt should close hard on the unfired round, since you're jamming the bullet into the lands.
If you're brass is halfway decent, you won't need to turn it. Find someone with a Neco gauge, or something similar, and check it out. If it doesn't vary too much, leave it alone.
FWIW, I shoot unprepped (except for flashhole and primer pocket) Winchester .22-250 brass in one of my Savages, and with 55 gr. Berger MEFs and H380, it'll agg in the mid-threes...
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