I am a fan of the .270 for hunting. I have taken a few deer with it up to 300yds and I am sure it will take deer at much longer ranges I just haven't tried it, but if that's rifle that you are building from and you are going to change the barrel anyway I beleve you could go with a different caliber because the bolt face is the same as many other cailbers. I am no expert and I am sure someone else will come along and give you some better advice.
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“The problem with socialism is that you eventually run out of other people's money.”
-Margaret Thatcher-
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