Alas, the kind of ammo normally used by civilians for self-defense is not very effective against anyone wearing high-quality body armor, which is a good thing if it's a police officer taking the hit, not so good if it's the bad guy. To penetrate body armor reliably, you really need armor piercing rounds from a rifle like those used by the military, though there are perhaps a few high-velocity, small caliber pistol rounds which
might work. Neither of the rounds you mention, Doug, would likely work worth a damn. Your only real chance then is to go for a head shot. Either of the rounds you mention will work quite effectively with that shot, one might argue.