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I can tell you that 2400 is much more at home in true magnum loads and is meant to run heavy bullets at high speed. Running a light-for-caliber bullet at a low to midrange speed is not the forte of 2400. For that, you'd likely use Unique, Universal or something a little more medium rate.
That's not to say that you can't TRY 2400. I think you'll find that it doesn't offer great performance in that role and you may experience some unburnt powder in your handgun.
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Attention Brass rats and other reloaders: I really need .327 Federal Magnum brass, no lot size too small. Tell me what caliber you need and I'll see what I have to swap. PM me and we'll discuss.
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