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A few things of note:
Caliber: You want a heavier caliber in case you need to shoot through a car door. Army tests with submachine guns have shown that 9mm sometimes has a problem penetrating car doors, and can deflect significantly, but .45 ACP goes through like a hot knife through butter.
Ammo type: You should consider using FMJ for the same reasons. You need something that will penetrate and hit the bad guy.
Gun type: You want a soft-recoiling gun for better control, as you may need to shoot it one-handed while driving. This also reduces the risk of accidentally dropping it.
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